Kirkuk University Journal-Scientific Studies

Abstract

4-Chloro acetyl amino sulphamethaoxazole (A1) was synthesized by the reaction of amino
sulphamethaoxazole with chloro acetyl chloride, Then refluxed with ammonium thiocyanate to obtain
thiazoldine-4-one (A
2) . (A2) was stirred with formaldehyde and various secondary amines to gain 5 novel
compounds Mannich bases(A
3-7
).and 2,5-Disubstituted thiazolidine-4-one (A
8-11) were synthesized by the
reaction of substituted benzyldehyd with Compound (A2) . The structure of the synthesized compounds are
confirmed by I.R,
1
H-NMR &
13
C-NMR spectra and Some chemical physical data