4-Chloro acetyl amino sulphamethaoxazole (A1) was synthesized by the reaction of amino
sulphamethaoxazole with chloro acetyl chloride, Then refluxed with ammonium thiocyanate to obtain
thiazoldine-4-one (A
2) . (A2) was stirred with formaldehyde and various secondary amines to gain 5 novel
compounds Mannich bases(A
3-7
).and 2,5-Disubstituted thiazolidine-4-one (A
8-11) were synthesized by the
reaction of substituted benzyldehyd with Compound (A2) . The structure of the synthesized compounds are
confirmed by I.R,
1
H-NMR &
13
C-NMR spectra and Some chemical physical data
A. Al-Badrany,K , S. Hamad,A and K. Al-Juboori,I . (2013). Synthesis of Some Mannich and 2,5-Disubstituted4-Thiazolidinone Compounds Derived from 4-amino Sulphamethaoxazole. Kirkuk Journal of Science, 8(3), 65-74. doi: 10.32894/kujss.2013.83421
MLA
A. Al-Badrany,K , , S. Hamad,A , and K. Al-Juboori,I . "Synthesis of Some Mannich and 2,5-Disubstituted4-Thiazolidinone Compounds Derived from 4-amino Sulphamethaoxazole", Kirkuk Journal of Science, 8, 3, 2013, 65-74. doi: 10.32894/kujss.2013.83421
HARVARD
A. Al-Badrany K, S. Hamad A, K. Al-Juboori I. (2013). 'Synthesis of Some Mannich and 2,5-Disubstituted4-Thiazolidinone Compounds Derived from 4-amino Sulphamethaoxazole', Kirkuk Journal of Science, 8(3), pp. 65-74. doi: 10.32894/kujss.2013.83421
CHICAGO
K A. Al-Badrany, A S. Hamad and I K. Al-Juboori, "Synthesis of Some Mannich and 2,5-Disubstituted4-Thiazolidinone Compounds Derived from 4-amino Sulphamethaoxazole," Kirkuk Journal of Science, 8 3 (2013): 65-74, doi: 10.32894/kujss.2013.83421
VANCOUVER
A. Al-Badrany K, S. Hamad A, K. Al-Juboori I. Synthesis of Some Mannich and 2,5-Disubstituted4-Thiazolidinone Compounds Derived from 4-amino Sulphamethaoxazole. Kirkuk J. Sci.. 2013;8(3):65-74. doi: 10.32894/kujss.2013.83421
