Herpes Simplex Virus-1(HSV-1) causes many diseases including encephalitis, meningitis, keratitis etc. ,also it infects the immunocompromised patients as leukemia and AIDS patients.

Herpes Simplex Virus-1(HSV-1) causes many diseases including encephalitis, meningitis, keratitis etc. ,also it infects the immunocompromised patients as leukemia and AIDS patients.
The study include (104) case of blood samples from thalassemic patients between 2008-2009. the anti HSV-1 IgM , anti Cytomegalovirus (CMV) IgM and anti Toxoplasma gondii IgM were detected in patient's serum using ELISA.
The results showed that the rate of anti HSV-1 IgM and anti CMV IgM in urban was higher than rural which was (8.65%) , also the rate of anti HSV-1 IgM and anti T. gondii IgM was equal in urban and rural which was (0.96%), where as the rate of anti T. gondii IgM only in urban was higher than rural which was (8.65%).
The results revealed that there was a significant difference between anti HSV-1 IgM ,anti T. gondii IgM and blood group .The rate of anti HSV-1 IgM and anti T. gondii IgM for patients with B and O blood groups was (0.96%) for both of them , and there was also significant difference between HSV-1 IgM , anti CMV IgM and blood group .The higher rate was in patients with blood group B it was (5.8%) and in patients with blood group O was (2.9%).
The higher rate of anti HSV-1 IgM was in patients with B blood group it was (2.9%),(4.8%) in male and female respectively .