Blood samples were collected from myocardial infarction patients and control groups in Ramady city / Anbar governorate – Iraq. Serum was used to know myocardial infarction effect on the lipid profile, three enzymes activity, proteins and urea . The results were showed the following: (a) Significant increment in cholesterol, triglyceride , LDL and VLDL, while we were observed significant decrement in HLD and urea. (b) Change in the electrophoretic bands of proteins by using polyacrylamide gel electrophoresis. (c) Significant increment in enzymes activity of CK , LDH , GOT and protein content in the myocardial infarction patients. (d) C-Reactive Protein was showed that 84% of MI patients gave positive results .