Abstract
This study had been designed to illustrate the relationship between immunological and biochemical abnormalities in patients with coronary heart disease (CHD) in Dohuk.
These patients were referred to the general Azadi hospital in Dohuk for investigation.
The present study include 80 patients with coronary heart disease (CHD) which consisting of 44 males (55%) and 36 females (45%). The Patients were divided into two groups, the first group included 42 (52.5%) patients with angina pectoris (AP), and the second group included 38 (47.5 %) patients with myocardial infarction (MI).In addition, 10 healthy volunteers were participate as control group. The age distributions of these groups were 56.4 ±1.43 for CHD patients, 52.66 ±1.204 for AP patients, 60.52 ±2.35 for MI patients and 54.9 ±2.167 for controls (healthy).
Two parameters level in serum of patients and healthy groups we study such as detection of C-reactive protein (CRP) using agglutination test and measurement of total cholesterol (C). The results revealed by statistical analysis the following data:-
1- It has been found that CRP was elevated in 66 (82.5%) patients with CHD which include 36 (85.71%) patients with AP & 30 (73.684%) patients with MI in comparison of healthy individuals 1 (10%) (p<0.05).
2- The level of total cholesterol was high in patients with CHD 5.75 mmol/L ± 0.14 which was 6.02 mmol/L ±0.25 in patients with AP & 5.44 mmol/L ±0.09 in patients with MI as compared with control (healthy) group 4.071 mmol/L ± 0.086 and the difference highly significant (P<0.05).
This result reflects the importance of using all parameters mentioned in this study to achieve good prognosis especially c-reactive protein in diagnosis of cardiac disease.
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