The study included 70 conditions of Hyperthyroidism and Hypothyroidism, in addition to 30 conditions of healthy women who consult Tigris Medical Rehabilitation hospital. Their symptoms proved through physiological tests of the thyroid gland. The tests included: Assessing the concentration of thyroid hormone in serum T4, assessing concentration of stimulating hormone thyroid gland in serum TSH. M biochemical tests included: sugar level, cholesterol level, triglycerides level, proteins level. And the effectiveness of the enzyme Aspartate transaminase (AST). The results showed the existence of significant low in the total level of protein in serum of women patient of thyroid deficiency, while no change was noted in disease hyperthyroidism and the level (P <0.05). While the survey showed significant increase in the level of total sugar in the blood serum of women with excess gland, while there has been no change total sugar level in blood serum of women with thyroid deficiency in level of (P <0.05). The search results showed high level of triglycerides in hypothyroidism at level of (P <0.05). The results showed significant increase of effect of enzyme AST in both symptoms hyperthyroidism and hypothyroidism at level (P <0.05). The conclusion of the study is there is low protein level for women patient of hypothyroidism, increase of sugar level in blood serum in women patient of hyperthyroidism, high level glycerides and cholesterol in women patient of hypothyroidism, high level of AST effect for women patient of hypothyroidism and hyperthyroidism.