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Construction of New Coated Carbon Electrodes for Determination of Sildenafil Citrate Drug

    Aveen K. Mohammed Ali I. Khaleel Nawzad N. Ahmed

Kirkuk University Journal-Scientific Studies, 2020, Volume 15, Issue 2, Pages 1-16
10.32894/kujss.2020.15.2.1

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Abstract

In this research, new coated carbon electrodes were constructed and used for the determination of Sildenafil citrate (SILC) drug. The electrodes were constructed by preparing ion-pair for (SILC) with phosphotungstic acid (PTA) or phosphomolybdic (PMA) acid using   dibutyl phthalate (DBP) as a plasticizer. These electrodes showed good sensitivity towards SILC with linear range of (1.0´10-7-1.0´10-2) M, correlation coefficient, (0.9990), the life time (120) days, optimum temperature range (23-65) oC and optimum pH range (2-5) for both electrodes, limit of detection (5.055´10-8 and 5.116´10-8) M, slope (57.29 and 59.10) mV/decadefor SILC-PTA and SILC-PMA electrodes respectively. These electrodes were successfully applied for determination of SILC in pure and pharmaceutical preparation form(tablets) with recovery of not less than 98%.
Keywords:
    Coated carbon electrode Sildenafil citrate drug Potentiometry method
Main Subjects:
  • BioPhysics
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(2020). Construction of New Coated Carbon Electrodes for Determination of Sildenafil Citrate Drug. Kirkuk University Journal-Scientific Studies, 15(2), 1-16. doi: 10.32894/kujss.2020.15.2.1
Aveen K. Mohammed; Ali I. Khaleel; Nawzad N. Ahmed. "Construction of New Coated Carbon Electrodes for Determination of Sildenafil Citrate Drug". Kirkuk University Journal-Scientific Studies, 15, 2, 2020, 1-16. doi: 10.32894/kujss.2020.15.2.1
(2020). 'Construction of New Coated Carbon Electrodes for Determination of Sildenafil Citrate Drug', Kirkuk University Journal-Scientific Studies, 15(2), pp. 1-16. doi: 10.32894/kujss.2020.15.2.1
Construction of New Coated Carbon Electrodes for Determination of Sildenafil Citrate Drug. Kirkuk University Journal-Scientific Studies, 2020; 15(2): 1-16. doi: 10.32894/kujss.2020.15.2.1
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