Kirkuk Journal of Science

Kirkuk Journal of Science

Synthesis, Characterization and Evaluation Antibacterial Activity of Some Schiff Bases and (1,3-Oxazepine or Diazepine-4,7-Dione)

Document Type : Research Paper

Author
Chemistry Department, College of Education for pure Science, Kirkuk University, Kirkuk, Iraq.
Abstract
In this study, some of Schiff bases, 1,3-oxazepine-4,7-dione and 1,3-diazepine-4,7-dione compounds derived from terephthalaldehyde and substituted aniline have been prepared, Schiff bases (a1-5) which derived from terephthalaldehyde and substituted aniline have been reacted with maleic anhydride and phthalic anhydride to produce 1,3-oxazepine-4,7-dione compounds (b1-10). 1,3-oxazepine-4,7-dione compounds (b1-10) have been reacted with phenyl hydrazine to produce 1,3-diazepine-4,7-dione compounds (c1-10). The prepared compounds were characterized using physical methods, the precise analysis of elements (C.H.N), infrared (IR) and (1H NMR) spectroscopy. The reactions were monitored by. Thin Layer Chromatography (TLC). The antibacterial activity was evaluated for some of the synthesis compounds.ً.
Keywords
Subjects

Volume 14, Issue 2
Spring 2019
Page 249-272

  • Receive Date 01 June 2019
  • Revise Date 20 June 2019
  • Accept Date 25 June 2019