Abstract
This study includs the preparation and identification of four membered rings Hetrocyclic Compounds derived from Trimethoprim by reaction Schiffs, bases(1a-h)( prepared by reaction some aromatic aldehyde with Trimethoprim using Microwave technique) with chloro acetyl chlorid in the presence of triethylamine , the prepared compounds were identified by I.R spectroscopy and some of them by NMR spectroscopy and C.H.N.S micro analysis.