Kirkuk Journal of Science

Kirkuk Journal of Science

Synthesis, Characterization and Biological Investigation of Some New Hydroxy – 1,3,4 – Oxadiazole Derivatives

Authors
Abstract
study the solid compounds of hydroxy 1,3,4 – oxadiazoles have been synthesized by reaction of acid hydrazides with CS2 in the presence of KOH. All the prepared compounds are characterized by using elemental analysis (C, H, N and S) and spectroscopic IR, H1 – NMR and studied the biological activity on four antibacterial (gram +Ve and gram –Ve) and three antifungal organisms. 1,3,4 – Oxadiazole are important compounds because of its versatile biological action such as antimicrobial, antimalarial, anticonvulsant, hypoglycemic, also analgesic, anti – inflammatory and anticancer. In the present
Keywords

Volume 11, Issue 3
Summer 2016
Page 304-320

  • Receive Date 01 September 2016
  • Revise Date 20 September 2016
  • Accept Date 25 September 2016