دراسة علاقة هرمون النمو بمستوى بعض الهرمونات التكاثرية وبعض المؤشرات لدى النساء العراقيات خلال دورات التلقيح الاصطناعي/الحقن المجهري

نوع المقالة : بحث

المؤلفون

1 قسم علوم الحياة،كلية العلوم، جامعة بغداد، بغداد، العراق.

2 قسم علوم الحياة، كلية العلوم، جامعة بغداد، بغداد، العراق.

الملخص

يعاني ما يقدر بـ 12-20% من الأزواج من العقم، ويوصف بأنه عدم القدرة على الحمل بعد عام من المحاولة. حوالي ثلث هؤلاء الأزواج يعانون من العقم بسبب العوامل الأنثوية، وثلث آخر يعانون من العقم بسبب العوامل الذكورية. قد يختبر الأزواج مزيجًا من الاثنين في الثلث المتبقي. وتنقسم إلى مجموعتين، العقم الاولي والثانوي. بلغ عدد المشاركين 60 مشاركًا، 30 منهم من النساء الأكبر سناً (> 35 عامًا) و 30 منهم من النساء الأصغر سنًا (أقل من 35 عامًا). في هذه الدراسة أظهرت النتائج وجود علاقة إيجابية ذات دلالة إحصائية عالية بين هرمون النمو وكل من المصل والسائل الجريبي (FF).
FSH (0.84, 0.81 mIU/ML), LH (0.76, 0.74 mIU/ML) and AMH(0.89, 0.86 mIU/ML), وكان هناك ارتباط إيجابي عالي المعنوية بين هرمون النمو وعدد البويضات المستخرجة (mIU/ML 0.47, 0.46), تم العثور على علاقة غير ربط سلبية بين هرمون النمو وعدد حالات الإجهاض (mIU/ML -0.10, -0.14). والجدير بالذكر أن الغالبية العظمى من تقييمات مستويات هرمون النمو في المصل والسائل الجريبي كشفت عن وجود علاقة إيجابية ذات دلالة إحصائية مع FSH، LH، AMH، وتواتر حالات الإجهاض، واسترجاع البويضات ومدة العقم. تشير هذه النتائج إلى وجود علاقة إيجابية قوية بين هرمون النمو وخصوبة الإناث. ونتيجة لذلك، هناك حاجة إلى الكثير من الأبحاث لتقييم وتقدير أهمية مستويات هرمون النمو على خصوبة المرأة، والحصول على تقييم مبكر لمستوى الهرمون قبل البدء في برنامج علاجي يحتوي على هرمون النمو.

الكلمات الرئيسة

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السنة 18، العدد 4
كانون الأوّل / ديسمبر 2023
الصفحة 65-73
  • تاريخ الاستلام: 06 كانون الأوّل / ديسمبر 2023
  • تاريخ التعديل: 24 كانون الأوّل / ديسمبر 2023
  • تاريخ القبول: 24 كانون الأوّل / ديسمبر 2023