Keywords : antibacterial


In- Vitro Study of Antibacterial Properties and Phytochemical Contents of Coriander Seeds Against Five Bacteria.

Arjan Aydin Zeynel; Ulker Abdul-baqi Abbas

Kirkuk University Journal-Scientific Studies, 2019, Volume 14, Issue 2, Pages 1-18
DOI: 10.32894/kujss.2019.14.2.1

In an effort to highlight the role of digestion and maceration methods to determine the strength of antibacterial effect and phytochemical elements of coriander seeds aqueous and methanolic extracts. Five concentrations (20, 40, 80, 160 and 320 mg/ml) of four extracts (aqueous by maceration, aqueous by digestion, methanolic by maceration and methanolic by digestion) were utilized against five clinically isolated bacteria (Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aerogenosa and Acenitobacter baumani), and compared with ciprofloxacin and cefotaxime discs as control. Agar well diffusion technique was employed to clarify the antibacterial activity of the extracts' concentrations relaying on quantifying the diameter of inhibition zone (IZ) in millimeter. The bioactive chemical compounds of four extracts were specified by means of conventional systems. In the main, all extracts inhibited the growth of every bacterial species starting from (80) mg/ml concentration, forming IZs' with various measurements that their expansion was drawing upon the rising of extracts' concentrations. The IZs that proceeded from (160, 320) mg/ml concentrations were larger than that come out from cefotaxime. The maceration extracts declared their embracement of alkaloids, and their impact were vigorous compared with the extracts of digestion which marked by comprising the tannins and flavonoids in aqueous and methanolic extracts one by one. The most susceptible bacterium to ethanolic extracts was S. aureus. It could be benefiting from coriander seeds for treatment of bacterial infections through extraction the best active phytoconstituents by using both of suitable extraction technique and solvents together. .

Some new Schiff Base Complexes of copper (II) and Their Biological Screening

A.J. Al-Shaheen; I.J. Sallomi; S.A. Al-Sabaawi

Kirkuk University Journal-Scientific Studies, 2013, Volume 8, Issue 2, Pages 48-58
DOI: 10.32894/kujss.2013.79700

Homodinuclear complexes of Cu(II) metal ions with three Schiff base ligands have been prepared andcharacterized.Theligandsare:
dibenzoinlidenemalonoyldihydrazide(BMDH4),dibenzoinlidenesuccinyldihydrazide(BSDH4)and dibenzoinlidene phthaloyldihydrazide (BPDH4) which are obtained by the reaction of malonoyldihy drazide,succinyl dihydrazide and phthalolyldihydrazide with benzoin in mole ratio1:2 The preparation of the complexes was carried out in both neutral and basic media and have been characterized by different phys- icochemically and they found to formulas[Cu2(LH4)2]X4 in neutral medium and [Cu2L2]in basic medium, respectively. Octahededral structure has been suggested for all the hexacoordinated complexes Furthermore thecomplexes have been found to be biologically active as demonstrated by antibacterial screening against four human pathogenic bacterial stains. It has been found that the complexes were more effective agent than the ligands (where X= Cl-,NO3- ).

Antibacterial activity of ethanolic and methanolic extracts of green algae against some bacteria

Hassan A. AbdAlredha; Salah S. Zain Al Abdeen; Raaer Ibrahim Kassim

Kirkuk University Journal-Scientific Studies, 2012, Volume 7, Issue 2, Pages 41-61
DOI: 10.32894/kujss.2012.63264

The study was conducted to evaluate the antibacterial , activities of the extracts of the green algae, Chlorella vulgaris.
The pathogenic bacteria was isolated and identified from different samples including urine , stool , ear swab , wound swab and one bacteria isolated from soil .The multiple antibiotic resistance of bacterial isolates was examined against different antibiotics used in this study , the results showed that Staphylococcus aureus E4 resistant to six antibiotics, where as Klebsiell pneuomoniae U1 appear resist to all antibiotics used .
The growth phases of algae were determined and the cultures were harvested at the end of logarithmic phase .The cultures of green algae gave 0.047gm/L..
Results showed that the extraction by ethanol 80% at 80Cْ for 4 h is the best method for extraction of crude materials from green algae .In spite of the appearance of some activity in the stationary phase ,results indicated that ethanolic extract of the green algae at the end of logarithmic phase have broad effects on gram positive and gram negative bacteria,which are resistant to different antibiotics .The results also showed that MIC of of ethanolic extract from the green algae Chlorella vulgaris is 0.9 mg/ml aginst E.coliU3 and Staphylococcus aureua U2.